How Revaginal Ovules restores hydration, pH and vaginal microbiome
Over 50% of postmenopausal women live with mild to severe vaginal dryness. The figure is also rising among younger women, yet the condition remains chronically undertreated: not for lack of products, but for lack of products truly designed to address its complexity.
Vaginal dryness is not merely a hormonal issue. Altered pH, depleted microbiome, peripheral vasoconstriction: three distinct mechanisms that compound and feed each other. It requires a response that acts on all of them simultaneously. Revaginal Ovules is born from exactly this rationale: a Class IIa medical device with a clinically validated multi-level formulation.
The Science Behind Vaginal Dryness
Maintaining an acidic vaginal pH, between 3.5 and 4.5, is the condition that allows Lactobacilli to survive, local defences to function, and the mucosa to stay hydrated. When pH rises, the environment becomes susceptible to infections, the flora becomes impoverished and natural lubrication decreases. Untreated consequences include dyspareunia, chronic itching, recurrent infections and, in prolonged cases, tissue atrophy.
The review published in the EPMA Journal (Goncharenko et al., 2019) documented how excessive vasoconstriction and systemic deregulation of hydration are significantly more frequent in women with vaginal dryness compared to healthy controls (p < 0.05). The condition is not a hormonal problem with nuances: it is a multifactorial problem requiring a multi-level solution.
Revaginal Ovules: The Synthesis of Science and Formulation
In this context, Revaginal Ovules, a Class IIa medical device manufactured in Italy by Gruppo Farmaimpresa, is introduced. The 2 g vaginal ovule formulation is built around ingredients with complementary mechanisms of action: hydration, lubrication, pH restoration and microbiome support in a single treatment cycle.
This approach makes it possible to concentrate the action on all relevant parameters, rather than treating one symptom at a time.
How do the ingredients in Revaginal Ovules work?
- Sodium hyaluronate: prolonged mucosal hydration with water-binding capacity superior to conventional polymers. Reduces burning and supports local tissue trophism.
- Polycarbophil: mucoadhesive agent that prolongs the permanence of the formulation, progressively lowers pH and promotes the controlled release of the other components.
- Lactic acid: rapid restoration of pH to the physiological value of 3.5, fundamental for Lactobacilli vitality and resistance to infections.
- Semi-synthetic triglycerides: direct mucosal lubrication for an immediate improvement in comfort.
- 18-beta-glycyrrhetinic acid + Vitamin E: support for cellular integrity and tissue protection with action on epithelial membranes.
- Tea tree oil: natural preservative in line with a formulation oriented towards tolerability and biocompatibility.
Why choose Revaginal Ovules?
- Documented efficacy: prospective clinical study on 20 subjects (VSQ Questionnaire, 10 days): dryness -90%, burning -100%, irritation -90%, itching -100%, pain -68%, intimate desire +64%.
- Multi-level action: hydration, lubrication, pH modulation and microbiome support in a single ovule. Protocol: 1 ovule per day, before rest, for 5-7 consecutive days.
- Certified safety: non-cytotoxic, non-irritating, non-sensitising. Compatible with barrier contraceptives.
- Industrial quality: manufactured in Italy, ISO 9001, ISO 13485, CE marking.
For whom is it indicated?
- Vaginal dryness from hormonal causes: in menopause, perimenopause or endocrine conditions in reproductive age.
- Non-infectious vulvovaginal discomfort: burning, itching, pain during intercourse.
- Support in infectious conditions: in combination with antifungal or antibacterial therapies to restore local balance.
- Maintaining vaginal balance over time: ongoing support for women with fragile microbiome or reactive mucosae.
The approach to vaginal health requires solutions that go beyond the symptom. Revaginal Ovules responds with a formulation designed on scientific evidence, clinically validated and produced to the most rigorous standards.
Revaginal Ovules is available in Private Label or Ready to Market.
Scientific source: Goncharenko V, et al. Vaginal dryness: individualised patient profiles, risks and mitigating measures. EPMA Journal. 2019;10:73-79. DOI: 10.1007/s13167-019-00164-3
